- Alice, daughter of Ginger, in E.L. Koinsburg's The View from Saturday. She belongs to Julian Singh and is named after Alice from Alice's Adventures in Wonderland by Lewis Carol.
- Argos, the faithful dog of Odysseus in Homer's Odyssey.
- Baree, son of Gray Wolf and Kazan, in James Oliver Curwood's 1917 novel "Baree, Son of Kazan".
- Barnabas, the talking canine companion of first Destruction and later Delirium in The Sandman.
- Blanche, one of King Lear's dogs
- Blood, the main character's dog in the book A Boy and His Dog by Harlan Ellison.
- Bob, the title character in Agatha Christie's Dumb Witness
- Boots, narrator of Thy Servant a Dog by Rudyard Kipling
- Buck, the main character in Jack London's Call of the Wild
- Bulls-eye, Bill Sikes' dog in Oliver Twist
- Buster, Scottish Terrier belonging to Frederick Algernon Trotteville ("Fatty") in Enid Blyton's "Five Find-Outers" series of children's mystery novels
- Funny dog, [CoCo the Blogging Dog]http://www.cocothebloggingdog.com, blogs about life as a dog.
- Cafall, a dog belonging to King Arthur (occasionally spelled "Cabal")
- Cerberus from Greek Mythology, the three-headed hellhound of Hades.
- Ceril, the hellhound from Eva Ibbotson's The Haunting of Hiram.
- Chief from The Fox and the Hound
- Copper from The Fox and the Hound
- Cujo the St. Bernard in the novel by Stephen King (later a movie)
- Dingo, in A Captain at Fifteen by Jules Verne
- Dingus, in Dingus Dreaming and The Canine Condition by Alex A. Vardamis
- Dog, the hellhound from "Good Omens" by Terry Pratchett and Neil Gaiman
- Dog that did nothing in the night-time, unnamed, this "curious incident" providing a clue in the Sherlock Holmes story The Adventure of Silver Blaze by Sir Arthur Conan Doyle.
- Duchess, the dog who thought she swallowed a patty pan, in Beatrix Potter's The Pie and the Patty Pan
- Effdee, the protagonist on the fantasy webcomic Anema: Age of the Robots
- Einstein, the golden retriever in Dean Koontz's book Watchers
- Fang, Grip and Wolf. Farmer Maggot's guard dogs in J. R. R. Tolkien's The Lord of the Rings
- Fang, Hagrid's dog, a boar-hound (a Mastiff) in the Harry Potter books: (in the movies, Fang is a Neapolitan Mastiff)
- Fidele in Gogol's Diary of a Madman
- Fluke, the title character in Fluke by James Herbert
- Fluffy, the three-headed dog (similar to Cerberus) in Harry Potter and the Philosopher's Stone
- Fly, the collie who befriends Babe the piglet in Dick King-Smith's The Sheep-Pig, the basis for the film Babe
- Garm, in J.R.R. Tolkien's Farmer Giles of Ham
- Gaspode, an unusually clever dog who talks, in various Discworld novels by Terry Pratchett
- Ginger, the dog of Nadia Diamondstien in E.L. Koinsburg's The View from Saturday.
- Ginger Pye, the dog of the Pyes in the book Ginger Pye.
- Hank, a cowdog in the Hank the Cowdog series by John R. Erickson
- Harold, Howie, Dawg, Hamlet, Georgia, Linda and Bob, dogs who appear in theBunnicula books by James Howe.
- Hound, the Penderwicks dog in The Penderwicks: A Summer Tale of Four Sisters, Two Rabbits and a Very Interesting Boy by Jeanne Birdsall.
- "Hound of the Baskervilles (The)", a Sherlock Holmes tale by Sir Arthur Conan Doyle with the famous line, "They were the footprints of a gigantic hound!"
- Huan, The great wolfhound of Valinor, friend and helper of Beren and L?thien, in J. R. R. Tolkien's novel The Silmarillion
- Hundred and One Dalmatians (The) by Dodie Smith, subsequently made into a movie by Walt Disney
- Jack from Little House on the Prairie series by Laura Ingalls Wilder.
- Jack from The Last Dog on Earth
- Jasper, Max de Winter's spaniel at Manderley in Daphne du Maurier's Rebecca (novel)
- Jenny, the star of Maurice Sendak's Higglety-Pigglety Pop, or, There Must Be More To Life
- Jerry, eponymous hero of Jack London's Jerry, Dog of the Islands
- Jip, the lapdog of Dora Spenlow, David Copperfield's first wife (Charles Dickens).
- Jip, one of Doctor Doolittle's animal companions in the books by Hugh Lofting
- John Joiner, the terrier who rescued Tom Kitten from being made into a pudding by rats in Beatrix Potter's The Roly-Poly Pudding
- Kashtanka, the main character in Anton Chekhov's short story of the same name (full text)
- Kazak, the hound of space, from The Sirens of Titan by Kurt Vonnegut.
- Kazan, the wolf dog in James Oliver Curwood's 1914 novel "Kazan the Wolfdog".
- Kep, the Collie, from Beatrix Potter's The Tale of Jemima Puddle-duck and other books
- Krypto, a white dog from the planet Krypton who was shot to Earth in a test rocket by Jor-El and subsequently found by young Clark Kent, his original owner on Krypton.
- Laddie (a send-up of Lassie (qv)) who stars in Discworld alongside Gaspode
- Laska in Leo Tolstoy's Anna Karenina
- Lassie, a collie, from the novel Lassie Come Home upon which the movie was very loosely based
- The Learned English Dog (LED) in Thomas Pynchon's Mason & Dixon
- Loony, the mischievous black spaniel belonging to Snubby in Enid Blyton's Barney Mystery series of mystery novels
- Luath, the Labrador Retriever from The Incredible Journey
- Madgie in Gogol's Diary of a Madman
- The "mastiff bitch" in Coleridge's Christabel who howls as Geraldine enters the castle.
- Montmorency from Jerome K. Jerome's Three Men in a Boat.
- Mouse, Harry's dog in The Dresden Files
- Nana, the Newfoundland dog in Peter Pan by J. M. Barrie
- Nero, the St. Bernard who comes to live with the Wilders in Laura Ingalls Wilder's The First Four Years
- O'Connor in Watt by Samuel Beckett
- Old Dan and Little Ann are Red Tick Hounds from Where the Red Fern Grows
- Olive, the Other Reindeer, from the book by Vivian Walsh and J. Otto Siebold, subsequently in the television special produced by Matt Groening
- Orson, the black Labrador retriever of Chris Snow in Dean Koontz's novels Seize the Night and Fear Nothing
- "Padfoot", or the nickname commonly referring to Sirius Black's animagus dog form in the Harry Potter novels by J. K. Rowling.
- Perezvon, another name for Zhucka (see below)
- Pickles, the terrier who kept shop with Ginger the cat in Beatrix Potter's Ginger and Pickles
- Piggy in Gone to the Dogs
- Pilot, Mr. Rochester's dog from Charlotte Bront?'s Jane Eyre
- The Poky Little Puppy of the children's book written by Janette Sebring Lowry and illustrated by Gustaf Tenggren
- Pippin, from the Pippin and Mabel series of picture books by K.V. Johansen
- Prince Terrian, Leslie Burke's (and the Burke parents') dog in the novel and 2007 movie, Bridge to Terabithia.
- Pugnax, a literate mutt who is the associate of the Chums of Chance in Thomas Pynchon's "Against the Day"
- Ralph the famous blue dog living in North Tonawanda, NY
- Ribsy, companion of Henry Huggins and character in numerous novels for young readers by Beverly Cleary
- Rowf, a black mongrel, one of the heroes of The Plague Dogs by Richard Adams
- Roy, Professor Presbury's wolfhound, attacks the professor at intervals thus providing a clue in the Sherlock Holmes story The Adventure of the Creeping Man by Sir Arthur Conan Doyle.
- Rumbo, a man reincarnated as a red setter (and subsequently as a red squirrel) in Fluke by James Herbert
- Sammy (Samson), a dog belonging to Downer, one of the house masters in P.G. Wodehouse's Mike and Psmith
- Scamper, golden spaniel belonging to Peter and Janet in Enid Blyton's Secret Seven series of young children's mystery novels
- Searchlight, the heroic sled-dog who pulled Little Willy's sled in the short novel Stone Fox by John Reynolds Gardiner.
- Sharik, the stray dog in Mikhail Bulgakov's novel Heart of a Dog who takes human form after a human pituitary gland and testicles were implanted into his body
- Sirius, eponymous hero of the science fiction novel by Olaf Stapleton, the result of an experiment to produce a dog with something like human intelligence.
- Snitter, a fox terrier one of the heroes of The Plague Dogs by Richard Adams
- Sweetheart, one of King Lear's dogs
- The dogs of The Tale of Little Pig Robinson by Beatrix Potter: Bob the Retriever; Gypsy; Pirate and Postboy the Greyhounds; Stumpy; Timothy Gyp the Sheepdog; and Tipkins
- Timmy: The fifth member of Enid Blyton's Famous Five
- The unnamed narrator of Franz Kafka's short story, Investigations of a Dog (1922)
- Thor, German Shepherd in the horror novel of the same name. It was eventually made into a film called Bad Moon
- Tiger, the dog belonging to the title character in The Narrative of Arthur Gordon Pym of Nantucket by Edgar Allan Poe and its sequel, An Antarctic Mystery by Jules Verne
- Tim Johnson, the rabid dog shot by Atticus Finch in the Pulitzer Prize-winning novel To Kill a Mockingbird by Harper Lee
- Timothy / Timmy / Tim (all three names are found interchangeably), George Kirrin's mongrel in Enid Blyton's Famous Five series of children's adventure novels
- Toby, the dog used by Sherlock Holmes in The Sign of Four by Sir Arthur Conan Doyle
- Top, the dog of Cyrus Smith in Jules Verne's The Mysterious Island
- Toto in The Wonderful Wizard of Oz by L. Frank Baum
- Trey, one of King Lear's dogs
- Tricki Woo, Mrs. Pumphrey's pekingese in If only they could talk (Book title in UK. All creatures great and small in the U.S.) by James Herriot
- Ugolina, malevolent and spooky prowler of pre-War Lisbon, in Jose Saramago's novel The Year of the Death of Ricardo Reis
- Valetka, in Turgenev's story "Yermolay and the Miller's Wife"
- What-a-Mess, Afghan Hound puppy in the Frank Muir stories
- White Fang, the main character in Jack London's book of the same name
- Wiggins, the heroine Maria's dog in The Little White Horse
- Winn-Dixie, from the book Because of Winn-Dixie by Kate DiCamillo and the 2005 film of the same name
- Yellow Dog Dingo, dog in Rudyard Kipling's Just So Stories
- Zelda Van Gutters, the "roving reporter" of Nickelodeon Magazine
- Zhucka in Dostoyevsky's Brothers Karamazov </p>